However, h.

Research team led by scientists from the Chinese University in Hong Kong released results this week, shows how bacteria,

Helicobacter Pylori, which causes more than half

worldwide and has been involved in eons managed to turn acidic environment of the human gut, where it can flourish. In his article in the Journal of Biological Chemistry paper weeks, the scientists say that the information they received about reasonable employment pathogen acid neutralizer can inform those developing new drugs to ease

H. pylori "with effects around the world. H. pylori

are the only known bacteria to thrive in the human stomach. It remains unclear how pathogens are transmitted, although researchers suspect that they may be spread through contaminated food or water. Damage to the bacteria to the intestinal mucosa allows stomach acid eating away the sensitive lining of the body, causing ulcers. Although more than half the world's population has the infection, for reasons still not entirely clear majority will never develop ulcers. In fact, existing antibiotics can cure 80 to 90 percent of ulcers caused by infection. However, H. pylori

for many years are becoming increasingly resistant to antibiotics. Some experts attributed that resistance that doctors prescribe antibiotics quickly to kill him, even if patients do not exhibit symptoms. There is an urgent need to develop new drugs and alternative strategies against helicobacter infection >> << to spread resistance to antibiotics out of control, said John Fong, lead author of JBC papers and PhD Chinese University of Hong Kong, whose research focused on the biochemical composition of protein complexes that promote the survival of H. pylorus century. This ability of the pathogen to persist in the acid bath in the stomach of strattera dosage a man who made him so successful, though harmful, vector, said Fong. The key is to use the enzyme urease to neutralize stomach acid, he explains. H. pylori

produce urease to promote dissolution of urea, natural chemicals in the body, so that urea can release ammonia to the gut environment in which pathogens can flourish. But, unlike most other enzymes urease not begin to do its work immediately after the bacteria is carried out, instead of two nickel ions must be delivered to him, and then the enzyme can mature, so to speak, and thus allow

H. pylori

begin their destructive work. As H. pylori survival

depends on the active urease, a matter of life or death for the pathogen to provide nickel ions delivered urease, said Kam-Bo Wong, a professor who led the project in the institution. .